KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F1
All Species:
15.45
Human Site:
T207
Identified Species:
28.33
UniProt:
Q01094
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01094
NP_005216.1
437
46920
T207
G
G
R
L
E
G
L
T
Q
D
L
R
Q
L
Q
Chimpanzee
Pan troglodytes
XP_524538
437
47536
G211
P
G
K
Q
Q
Q
L
G
Q
E
L
K
E
L
M
Rhesus Macaque
Macaca mulatta
XP_001103717
502
53768
T272
S
G
R
L
E
G
L
T
E
D
L
R
Q
L
Q
Dog
Lupus familis
XP_542963
571
61192
T342
S
G
R
L
E
G
L
T
Q
D
L
R
Q
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61501
430
46305
T202
G
K
R
L
E
G
L
T
Q
D
L
Q
Q
L
Q
Rat
Rattus norvegicus
Q62814
300
33206
V81
A
G
C
N
T
K
E
V
I
D
R
L
R
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
I219
L
E
V
Q
K
R
R
I
Y
D
I
T
N
V
L
Chicken
Gallus gallus
Q90977
403
43534
E184
S
S
R
Q
R
L
L
E
K
E
L
R
D
L
Q
Frog
Xenopus laevis
NP_001090608
426
47125
S199
S
S
R
Y
Q
S
V
S
K
E
C
Q
N
L
E
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
Q210
G
L
P
S
P
A
M
Q
S
H
S
L
A
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
A334
E
R
S
R
H
I
E
A
D
S
L
R
L
E
Q
Honey Bee
Apis mellifera
XP_396223
416
46049
W197
K
S
K
N
N
I
Q
W
K
G
G
Q
L
P
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
I184
V
L
E
G
I
K
L
I
T
K
K
S
K
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.7
86
70.9
N.A.
84.6
23.1
N.A.
39.9
59.9
49.8
37.2
N.A.
20.6
29.7
N.A.
38.4
Protein Similarity:
100
54.4
86.2
72.6
N.A.
88.5
37.9
N.A.
51.2
70
63.3
53.7
N.A.
31.5
46.4
N.A.
54.2
P-Site Identity:
100
33.3
86.6
93.3
N.A.
86.6
13.3
N.A.
6.6
40
13.3
6.6
N.A.
20
0
N.A.
6.6
P-Site Similarity:
100
66.6
93.3
93.3
N.A.
93.3
20
N.A.
26.6
53.3
60
20
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
47
0
0
8
0
0
% D
% Glu:
8
8
8
0
31
0
16
8
8
24
0
0
8
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
39
0
8
0
31
0
8
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
16
0
16
8
0
8
0
0
0
0
% I
% Lys:
8
8
16
0
8
16
0
0
24
8
8
8
8
0
0
% K
% Leu:
8
16
0
31
0
8
54
0
0
0
54
16
16
54
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
16
8
0
0
0
0
0
0
0
16
8
16
% N
% Pro:
8
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
24
16
8
8
8
31
0
0
24
31
0
47
% Q
% Arg:
0
8
47
8
8
8
8
0
0
0
8
39
8
8
0
% R
% Ser:
31
24
8
8
0
8
0
8
8
8
8
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
31
8
0
0
8
0
0
0
% T
% Val:
8
0
8
0
0
0
8
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _